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The Detroit Lions are expected to win their game versus the Kansas City Chiefs at 8:20 p.m. ET on Sunday, Oct. 12, according to our computer projections. If you're seeking additional projections on the final score, spread, and point total, we list those numbers below.
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Chiefs vs. Lions Game Info and TV Channel
- When: Sunday, October 12, 2025 at 8:20 p.m. ET
- Where: GEHA Field at Arrowhead Stadium in Kansas City, Missouri
- TV: NBC
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Listen to the game on 96.5 The Fan
Chiefs vs. Lions Odds and Betting Info
- Spread favorite: Chiefs (-2.5)
- Moneyline: Chiefs (-143), Lions (+121)
- Total: 52 points
Chiefs vs. Lions Prediction
- Pick ATS: Lions (+2.5)
- Pick OU: Under (52)
Prediction:
Lions 27 - Chiefs 25
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Chiefs vs. Lions Betting Insights
- The Chiefs have covered twice in five matchups with a spread this season.
- The Lions have covered four times in five chances against the spread this year.
- Kansas City has covered the spread once this season (1-2 ATS) when playing as at least 2.5-point favorites.
- Detroit has been an underdog by 2.5 points or more once this season, and covered the spread.
- A total of three out of five Chiefs games this season have gone over the point total.
- Lions games have hit the over three out of five times this year.
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